ZONESUN
ZONESUN ZS-AFY2 Automatic Prefilled Syringe Filling Stoppering Machine
ZONESUN ZS-AFY2 Automatic Prefilled Syringe Filling Stoppering Machine
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$64,000.00 USD
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$64,000.00 USD
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ZONESUN ZS-AFY2 Automatic Double-Head Prefilled Syringe Vacuum Filling and Stoppering Machine
The ZONESUN ZS-AFY2 is an automatic double-head prefilled syringe filling and stoppering machine designed for nest-based prefilled syringe (PFS) production. It automatically completes denesting, syringe feeding, vacuum filling, vacuum stoppering, and product discharge in a single process.
All product-contact parts are made of SUS316L stainless steel and medical-grade silicone, meeting GMP requirements. With high filling accuracy±1% filling accuracy, a filling range of 0.3–10 ml, and speeds of 1200–1500 syringes per hour, it is ideal for pharmaceutical and cosmetic applications requiring sterile, bubble-free filling of low to high-viscosity liquids.
Parameter
- Model: ZS-AFY2
- Machine Voltage: 380V/220V, 50/60 HZ
- Machine Power: 3.5 KW
- Filling Pump: Ceramic Plunger Pump
- Filling Heads Quantity: 2
- Filling Range: 0.3-10 ml (Based on Filling Material)
- Filling Accuracy: ⩽ ±1%
- Working Capacity: 1200-1500 PFS/H
- Compressed Air: 0.55-0.75 Mpa, 15 L/S
- Machine Size: L 1090 × W 860 × H 1800 mm (Without Laminar Flow Hood)
- Machine Weight: 500 kg





Denesting Structure
Automatically removes syringes from nested tubs without damage or manual intervention, reducing contamination risks.
Automatically removes syringes from nested tubs without damage or manual intervention, reducing contamination risks.
Double Heads Vacuum Filling Structure
Equipped with ceramic pump, suitable for low & high viscosity liquid, widen application range & improve filling accuracy.
Equipped with ceramic pump, suitable for low & high viscosity liquid, widen application range & improve filling accuracy.
Vibratory Stopper Feeding System
Uses a SUS316L stainless steel bowl to orient and deliver stoppers automatically to the insertion position, reducing manual handling.
Uses a SUS316L stainless steel bowl to orient and deliver stoppers automatically to the insertion position, reducing manual handling.

Vacuum Stoppering System
Places stoppers under vacuum conditions to minimize particle generation and protect product sterility.
Places stoppers under vacuum conditions to minimize particle generation and protect product sterility.

Why Choose the ZONESUN ZS-AFY2?
- Denesting Structure: Automatically removes syringes from nested tubs without damage or manual intervention, minimizing contamination risks.
- Double Heads Vacuum Filling: Ceramic plunger pumps provide precise, wear-resistant dosing suitable for both low and high-viscosity liquids while eliminating bubbles.
- Vibratory Stopper Feeding: SUS316L stainless steel vibratory bowl automatically orients and feeds stoppers to the insertion station.
- Vacuum Stoppering System: Places stoppers under vacuum conditions to reduce particle generation and maintain product sterility.
- Intelligent PLC & Touch Screen: Real-time monitoring, parameter adjustment, and fault diagnostics for stable and user-friendly operation.
Core Benefits
- High Accuracy: Ceramic pumps deliver ±1% filling precision.
- Aseptic Processing: Vacuum filling and stoppering minimize contamination.
- Efficient Production: 1,200–1,500 syringes per hour with double-head design.
- Hygienic Design: SUS316L contact parts and quick-release components meet GMP standards.
- Versatile: Handles various syringe sizes and liquid viscosities.
Target Applications
Ideal for aseptic filling and stoppering of prefilled syringes in pharmaceutical, vaccine, and cosmetic industries. Suitable for various injectable liquids, vaccines, hyaluronic acid, and other sterile formulations.
